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ORIGINAL RESEARCH
with increased hormone receptor-positive breast cancer and decreased triple negative cancer in postmenopausal women, but higher BMI was associated with decreased hormone receptor-positive cancer in premenopausal women.3 However, when evaluating using WHR, it demonstrated higher incidence of all breast cancer subtypes in postmenopausal women
and increased premenopausal hormone receptor-positive tumors.3 Although we
did not demonstrate a difference in breast only examined obesity as BMI >30. Further investigation using WHR and tumor- further evaluate the impact of obesity in breast cancer.
The effect of weight loss in breast
cancer survivors has also been studied,
loss interventions in AA breast cancer survivors.8 It was found that although both programs resulted in weight loss, patients enrolled in community-based weight loss programs had a higher percent weight loss than those in self-guided programs and had greater body composition and behavioral changes.8 Although current weight-loss standards do not exist for reduction in breast cancer mortality, obesity and metabolic cancer outcomes. There are many studies that have demonstrated the success of implemented weight-loss programs in the breast cancer-patient population. Future investigations should focus on establishing weight-loss goals to improve breast implementation of weight-loss programs as part of all obese cancer patients’ care should be considered. Wiggins et al. performed
a registry-based population study looking
at the cancer incidence in patients who underwent bariatric surgery.9 Bariatric surgery has been established as an effective method of achieving sustained weight loss in obese patients.9 Wiggins et al. further
in overall cancer incidence compared to controls.9 in the incidence of breast cancer, further supporting the importance of weight loss in obese cancer patients.8
Our study is limited based on the retrospective nature. Data was not always available for all patients secondary to information not being available in the electronic medical record at that time.
Data was also not available if patients
did not receive their care at HFGCCRI. Further limitations include the sample size; of Caucasian patients compared to AA. Collection of data is ongoing to determine with a larger sample size.
In conclusion, all patients with hypertension, diabetes, and/or metabolic syndrome have worse breast cancer- were more likely to have metabolic syndrome, there was no difference in with metabolic syndrome based on race. factors for AA patients to improve breast Attention must be placed on management and prevention of obesity and its associated comorbidities to improve
CONTRIBUTING AUTHORS
■ JENNIFER BAYRON, MD, is a surgical resident at Christiana Care Health System.
■ JENNIFER SIMS-MOURTADA, PHD is a
Senior Clinical Scientist and Director of the translational breast cancer research program at the Helen F. Graham Cancer Center & Research Institute at Christiana Care.
■ DIANA DICKSON-WITMER, MD is Medical Director of the Breast Center at the Helen F. Graham Cancer Center & Research Institute at Christiana Care.
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