Page 19 - Delaware Medical Journal - November/December 2020
P. 19
ORIGINAL RESEARCH
and the incidence of cancer and overall mortality was greatest in the 30-39-year- old range (Table 2-1). Non-Hispanic African American females in Delaware had a higher incidence of cancer, including cervical cancer, compared to non-Hispanic African American females in the United States (Table 2-2). They did not have an increased incidence in mortality (Figure 1-2).
CONCLUSIONS
AYA oncology patients are truly a
oncology advances, particular attention needs to be drawn to this group of patients with regard to cancer biology, barriers to care, poor clinical trial enrollment, and cancer incidence and mortality trends. In an effort to focus on understanding patterns of cancer incidence and mortality in AYAs,
REFERENCES
dedicating a section to AYAs in the annual Delaware Cancer Incidence Report would be imperative.
Based on the 2011-2015 Cancer Incidence Report, non-Hispanic African American females in Delaware had
a higher incidence of cervical cancer compared to non-Hispanic African American females in the United States. As cervical cancer is preventable with screenings, efforts can be made to increase the awareness in Delaware for routine screenings. This supports that subsequent Delaware Cancer Registry Incidence Reports would provide helpful information for oncologists to better understand patterns of cancer diagnoses and mortalities for the AYA population; with this information, changes can be implemented to decrease cancer incidence among AYAs.
ACKNOWLEDGEMENTS
We thank Sumitha Nagarajan and Diane Ng with the Delaware Cancer Registry for providing case counts, calculating cancer
CONTRIBUTORS
■ KATIE PARISIO, DO is a third-year pediatric hematology/oncology fellow with research interests in adolescent and young adult oncology.
■ STEPHANIE GUARINO, MD, MSHP, FAAP is a pediatric hematologist/oncologist who is board certified in Internal Medicine and Pediatrics. Her clinical care and research efforts focus on adolescent and young adult oncology patients at Nemours, and adults with sickle cell disease at The Center for Special Health Care Needs at ChristianaCare.
1. Boissel N, Baruchel A. Acute lymphoblastic leukemia in adolescent and young adults: treat as adults or as children? Blood. 2018;132(4):351-361. doi:10.1182/blood-2018-02-778530
2. Keegan THM, Parsons HM. Adolescent angst: enrollment on clinical trials. Hematology. 2018;2018(1):154-160. doi:10.1182/ asheducation-2018.1.154
3. Husson O, Huijgens PC, Graaf WTA van der. Psychosocial challenges and health-related quality of life of adolescents and young adults with hematologic malignancies. Blood. 2018;132(4):385-392. doi:10.1182/blood-2017-11-778555
4. Wolfson J, Sun C-L, Wyatt L, Stock W, Bhatia S. Adolescents and young adults with acute lymphoblastic leukemia and acute myeloid leukemia: Impact of care at specialized cancer centers on survival outcome. Cancer Epidemiol Biomarkers Prev. 2017;26(3):312-320. doi:10.1158/1055-9965.EPI-16-0722
5. Curran E, Stock W. How I treat acute lymphoblastic leukemia in older adolescents and young adults. Blood. 2015;125(24):3702-3710. doi:10.1182/blood-2014-11-551481
6. O’Dwyer K, Freyer DR, Horan JT. Treatment strategies for adolescent and young adult patients with acute myeloid leukemia. Blood. 2018;132(4):362-368. doi:10.1182/blood-2017-12-778472
7. Wolfson J, Sun C-L, Kang T, Wyatt L, D’Appuzzo M, Bhatia S. Impact of treatment site in adolescents and young adults with central nervous system tumors. JNCI: Journal of the National Cancer Institute. 2014;106(8). doi:10.1093/jnci/dju166
8. Flerlage JE, Metzger ML, Bhakta N. The management of Hodgkin lymphoma in adolescents and young adults: burden of disease or burden of choice? Blood. 2018;132(4):376-384. doi:10.1182/blood-2018-01-778548
9. Fardell JE, Patterson P, Wakefield CE, et al. A narrative review of models of care for adolescents and young adults with cancer: barriers and recommendations. Journal of Adolescent and Young Adult Oncology. 2018;7(2):148-152. doi:10.1089/jayao.2017.0100
10. Barriers to Cancer Clinical Trial Enrollment. Cancer Therapy Advisor. Published May 17, 2019. Accessed January 20, 2020. https:// www.cancertherapyadvisor.com/home/tools/fact-sheets/cancer-patient-clinical-trial-enrollment-barriers-fact-sheet/
11. Keegan THM, Tao L, DeRouen MC, et al. Medical care in adolescents and young adult cancer survivors: what are the biggest access- related barriers? J Cancer Surviv. 2014;8(2):282-292. doi:10.1007/s11764-013-0332-4
12. The Delaware Cancer Registry - Delaware Health and Social Services - State of Delaware. Accessed January 21, 2020. https://dhss. delaware.gov/dph/dcr/home.html
13. Coughlin S, Clutter G, Hutton M. Chapter 6: Ethics in Cancer Registries, with Gayle G. Clutter and Mary Hutton. In: Ethics in Epidemiology and Public Health Practice. American Public Health Association; 2009. doi:10.2105/9780875531939ch06
Del Med J | November/December 2020 | Vol. 92 | No. 6 259
