Page 20 - Italian-American Herald - December 2023

ITALIAN-AMERICAN HERALD 20 ITALIANAMERICANHERALD.COM | DECEMBER2023
NEWS FROM ITALY
Strides made in research to slow pancreatic cancer
Pontiff: Anti-Semitism should have ended with Holocaust
ANSA
ROME – A team of Italian scientists have found one of the engines that drive cancer
of the pancreas, one of the most aggressive tumors, in a discovery that has enabled them to identify a therapeutic target to hopefully
slow the advance of the disease.
The research has been led by Milan’s
Istituto San Raffaele, with the Istituto
Telethon of gene therapy and the Università
Vita e Salute.
Also working on the project were the
universities of Turin and Verona, the French Institute For Health and Medical Research (INSERM), the Biopolis research center in Singapore and the University of Shanghai.
Favoring the growth of this form of tumor which is still very lethal, the ductal adenocarcinoma of the pancreas, is a special alliance between a particular type of immune cells, called IL-1beta+ macrophages, and
some very aggressive tumor cells, known for being linked to inflammation.
“It’s a sort of self-feeding vicious circle,”
said research leader Renato Ostuni, head of the Innate Immune System Genomics Lab at the Istituto Sr-Tiget and associate professor at the Università Vita-Salute San Raffaele.
“The macrophages make the tumor cells more aggressive, and the tumor cells reprogram the macrophages capable of favoring inflammation, and the progression of the disease.”
The authors of the research said: “We have taken a good step forward in the understanding of the biological processes underlying the disease. However, we are at a stage of pre-clinical research, still distant from
application in patients.
“The coming years will be essential to
identify the potentialities and the most appropriate modalities to act on this new therapeutic target.”
The project was backed by Fondazione Airc, Italy’s cancer research foundation, the European Research Council, and the Italian health ministry.
ANSA
ROME – Pope Francis has said he is bewildered by the continuation of anti- Semitism even after the Holocaust showed where it can lead.
“Anti-Semitism, unfortunately, remains hidden,” the Argentine pontiff said recently on Rai’s Tg1 news show. “I don’t know how to explain it and I have no explanation, it’s a
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fact that I see it and I don’t like it.”
“You can see it, for example, in young
people here and there protesting against Israel. It is true that this situation is very serious but there is always something anti-Semitic; and it is not always enough to see the Holocaust that took place in the
Second World War, these 6 million killed, enslaved, and it has not passed,” he said. “Unfortunately, it has not passed.”
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